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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. With regard to the privacy rule of the Health Insurance Portability and Accountability Act (HIPAA), which of the following statements is correct with regard to the use or disclosure of Protected Health Information (PHI) in clinical research?

A) If the data are being used for preparatory research, no written authorization or waiver is required.
B) If the data being used do not include the patient's name or health record number, no authorization or waiver is required.
C) A researcher may use or disclose PHI if the individual patient has provided written authorization or if a Waiver has been obtained from an IRB.
D) A researcher may use or disclose PHI if the individual patient has provided verbal consent.

2. A 58-year-old woman presents to the emergency department of a small rural hospital with recurrent chest pain that is unrelieved by three sublingual nitroglycerin tablets. Initial evaluation of her ECG and cardiac enzymes are consistent with non-STEMI. The woman is admitted for observation and given aspirin. Which of the following should be added to this patient's regimen to reduce her risk of death, MI, and recurrent ischemia?

A) Subcutaneous heparin
B) Subcutaneous enoxaparin
C) Intravenous t-PA
D) Oral warfarin

3. A patient presents to the emergency department with an acute Ischemic stroke. The symptoms have been present for just over an hour.
Which test would be most appropriate to help determine the patient's eligibility to receive t-PA?

A) Neurologic exam
B) MRI
C) CT scan
D) Cerebral angiogram

4. A 67-year-old patient is hospitalized for decompensated heart failure. The serum sodium concentration is 130 mEq/L on admission. Which of the following is the most appropriate approach to managing the patient's hyponatremia?

A) Conivaptan 20 mg intravenously over 24 hours
B) 0.9% NaCl 200 mL/h intravenously for 5 hours
C) 3% NaCl 50 mL/h intravenously for 5 hours
D) Restriction of both sodium and fluids

5. A 42-year-old woman is diagnosed with deep vein thrombosis. Heparin therapy is initiated with
5,000 units as a single bolus injection, followed by an initial infusion rate of 1,000 units/h. The aPTT measured 6 hours later is >150 sec. Which of the following would be the most appropriate action at this time?

A) Continue the infusion at 1,000 units/h, since the aPTT was drawn too early and is not useful.
B) Stop the infusion until the aPTT falls to <50 sec, and then resume at 750 units/h.
C) Stop the infusion for one hour, then resume at 750 units/h.
D) Administer protamine 5 mg, and decrease the infusion rate to 750 units/h.

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